Endocrine Abstracts

Introduction: Infertility is a classic consequence of prolactinoma in women. The treatment of hyperprolactinemia allows the restoration of ovulatory cycles and therefore of fertility in 80–90% of cases.Methods and materials: The study is a retrospective cohort study done over 17 years from 2000 to 2017. It includes 77 cases of prolactinomas among which 12 women had one or more pregnancies after the diagnosis of prolactinoma.Re...

Introduction: Autoimmune polyglandular syndrome (APS) is an autoimmune disorder that affects many endocrine glands. Until now four categories of APS are identified: APS-I includes at least two out of: mucocutaneous candidiasis, hypoparathyroidism and adrenocortical failure. APS-II, the most frequent, comprises of Addison’s disease, autoimmune thyroid disease and/or type 1 diabetes. APS-III is defined by the presence of autoimmune thyroid disease and other autoimmune disor...

Introduction: Turner syndrome (ST) affects 1/2500–1/4000 of female births, its association with congenital malformations is traditional, however the coexistence of hypopituitarism is exceptional. In this context, we report 6 patients; including 3 belonging to the same family and in whom the association of anterior pituitary insufficiency (IAH) to a ST was confirmed.Results: The average age of our patients was 17.2 years (11–31). The ST was sele...

IntroductionSubclinical Cushing’s syndrome (SCS) is an endocrine disorder characterized by an autonomous cortisol secretion in patients bearing adrenal adenomas in the absence of specific signs of hypercortisolism. The cortisol excess is known to be associated with metabolic comorbidities such as obesity, hypertension, glucose intolerance, and dyslipidemia increasing the incidence of cardiovascular events. The objective of this study was to describe...

IntroductionRecent studies in patients with Addison’s disease have shown that this condition, even if treated, is fraught with significant morbidity and even excess mortality. The objective of our study was to determine the deleterious effects of long-term glucocorticoid replacement mainly on the metabolic level.MethodsRetrospective study, carried out at the Endocrinology and Diabetology Department of H&...

BackgroundIt’s well known that smoking and diabetes are direct causes for serious health problems such as cancer, and atherosclerosis. It is suggested that smoking indirectly leads to atherosclerosis by influencing nutrient intakes as smokers tend to eat more fat and carbohydrates and less mono unsaturated fats and fiber than non-smokers. But no studies assessed the impact of tobacco on nutrition in diabetic patients.Aim<p...

IntroductionMasked arterial hypertension (HTAM) is a relatively recently described entity which gives patients with it the same cardiovascular risk as permanent hypertension. In this context, we report a prospective study including 53 patients in order to determine the prevalence and predictive factors of HTAM in diabetics.MethodsDescriptive prospective study of 53 patients treated in the endocrinology Diabet...

IntroductionMitochondrial diabetes (DM) is characterized by a broad spectrum of phenotypic and genotypic involvement. Among 86 patients with DM, we chose to study the peculiarities of syndromic DM diagnosed in three families in order to be able to establish a correlation between this diversity of phenotypic expression and the biomolecular substratum of the mitochondrial genome.ResultsThese are four patients (...

IntroductionAcute pancreatitis (AP) is the most common affection of the pancreas, it often leads to glycemic disorders. On the other hand, diabetic ketoacidosis (DKA) is associated with nonspecific increase in serum amylase levels. The aim of this study was to evaluate the clinical characteristics of acute AP concomitant with DKA.MethodsWe conducted a retrospective and descriptive analysis of clinical records...

IntroductionSolid pseudopapillary tumors (SPT) of the pancreas area rare exocrine pancreatic tumor behaving in a low-grade fashion, with limited local invasion risk and a rare metastatic evolution. They mainly affect young women. Their etiopathogenesis remains uncertain. We report the case of a 15-year-old boy, having congenital anomalies, who presented a solid and pseudopapillarytumour of the pancreas.Case report<p class="abst...